Jennifer Aniston and Courteney Cox No Longer ‘Friends’?

Jennifer Aniston and Courteney Cox had a "disagreement" that threatens to "destroy their relationship," Us Weekly reports.

The mag says the best friends "had a spat on Cox this spring's romantic liaison with her ​​costar Brian Van Holt rumor."

According to a source we Weekly, "Jen thinks Courteney cruel acts from running with this guy, but refusing to file the divorce papers" from her ex-husband David Arquette.

Cox alleged dalliance with Van Holt is supposed to be a "reminder of the sentence" when Aniston had met Brad Pitt with Angelina Jolie immediately after their separation.

"She hates watching Courteney do that,"says the "source".

Hmm ...

There are some problems with the story of the mag.

Cox and Van Holt have NEVER been in love.